Giovanni Muggiasca, merchant of Como, purchased the land between Cernobbio’s and Moltrasio’s borders in 1435 and built Villa Pizzo. In 1629, during the plague, the Muggiasca family took refuge in Villa Pizzo along with many others from nearby towns who gave structure to the villa and its gardens.
The villa housed many guests including Alessandro Volta – famous scientist who invented the electric battery.
Giovanni Battista Mugiasca, the last Mugiasca heir, bequeathed the villa to Sant’Anna Hospital when he died in 1842.
Later, Archduke Rainer of Austria became the villa’s owner and set the final layout for the English and Italian gardens with the help of Villoresi – a famous landscape architect. In 1848, the Viceroy left the villa.
In 1865, Madame Musard acquired the villa, re-decorated its interiors and also added touches of pink and yellow colors to the villa.
Since 1871, the Volpi-Bassani family own the villa. They built the family mausoleum and the new grand dock on the east of the villa.