Villa Carlotta was commissioned by Marquis Giorgio Clerici at the end of the 17th century, but it was only with the following owner that the villa reached its maximum splendor.
In 1801, Gian Battista Sommariva, a famous politician, businessman, and patron of arts, acquired Villa Carlotta, which, over the decades, became one of the most important stops of the Grand Tour. Intellectuals from all around Europe came to see the villa because of its fine art collection and its fascinating botanical gardens.
In the second half of the century, Princess Marianne of Orange-Nassau bought the villa and gave it to her daughter Charlotte, after whom the villa is named, as a gift to commemorate her marriage to Georg II, Duke of Saxe-Meiningen.
Georg was passionate about botany and made many improvements to the park, which became more and more famous for its botanical richness. After the First World War, Villa Carlotta was acquired by an organization that was established for the specific purpose of taking care of the property.